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慢性 胰腺炎

Overview

慢性胰腺炎以急性胰腺炎开始,当胰腺出现不可逆的瘢痕形成时,就会变成慢性胰腺炎. 有很多因素会增加一个人患这种疾病的风险, such as alcohol consumption, 吸烟, genetic factors and other conditions or traumatic events that injure the pancreas. 胰腺可能最终停止产生身体消化和吸收营养所必需的酶. 在晚期,这种疾病会导致胰腺失去产生胰岛素的能力.

Our approach to chronic pancreatitis

UCSF offers state-of-the-art care for a wide range of pancreatic disorders, including chronic pancreatitis. Treatment for chronic inflammation of the pancreas depends on the cause, severity of the patient's pain and effectiveness of previous treatment approaches.

We begin by managing nutrition and seeking to relieve pain. If patients don't respond to these treatments, we may consider surgical options. 我们的团队在最新的微创技术和术后护理方面训练有素.

加州大学旧金山分校是十大赌博平台排行榜上为数不多的几家十大赌博平台排行榜之一,外科十大赌博平台排行榜采用一种创新的手术方法,切除整个胰腺,同时移植患者自己的胰岛细胞. 这种手术可以减轻疼痛,同时保持身体分泌胰岛素的能力, which reduces the risk of surgically induced diabetes.

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迹象 & 症状

Most people with chronic pancreatitis experience pain in the back and abdomen. 在某些情况下, abdominal pain goes away as the condition advances, probably because the pancreas is no longer making digestive enzymes

体重减轻通常是慢性胰腺炎的症状,因为身体不能分泌足够的胰酶来分解食物,营养物质不能正常吸收. Poor digestion leads to excretion of fat, protein and sugar in the stool. 如果胰腺分泌胰岛素的细胞被破坏,糖尿病就可能发生.

诊断

慢性胰腺炎的诊断通常可以完全基于你的症状和病史. Endoscopic retrograde cholangiopancreatography (ERCP), computerized tomography (CT) scans, and endoscopic ultrasound also can help your doctor make a definite diagnosis.

胰腺功能测试有助于确定你的胰腺是否仍在制造足够的消化酶. In more advanced stages of the disease when diabetes and malabsorption occur, your doctor may recommend blood, urine and stool tests.

治疗

Treatment of chronic pancreatitis depends on the cause of the disease, severity of the associated pain and effectiveness of former treatment approaches. 治疗的第一步重点是减轻疼痛和吃高碳水化合物和低脂肪的饮食. It is essential to stop drinking alcohol entirely.

如果你的胰腺分泌的酶不足,你的十大赌博平台排行榜可能会给你开一些胰酶,让你在吃饭的时候服用. 补充酶应该每餐服用,以帮助你的身体消化食物和恢复一些体重. 如果你有糖尿病,可能需要胰岛素和其他药物来控制血糖水平.

手术

对于无法通过药物或其他方法缓解疼痛的患者,有许多外科手术方法可供选择. 手术 may involve removing stones from the pancreas, draining blocked ducts, or partial or entire removal of the pancreas.

胰腺切除术

A partial pancreatectomy involves removing part of the pancreas, such as the body or tail, during a Puestow or Whipple procedure. A total pancreatectomy involves removing the entire pancreas. 而当所有其他治疗都失败时,全胰切除术通常能有效地缓解患者的疼痛, it induces permanent diabetes, 要求患者在他们的余生中注射胰岛素或使用胰岛素泵. 这是因为胰腺含有朗格汉斯胰岛——也被称为胰岛或胰岛细胞——它调节身体的血糖水平.

加州大学旧金山分校的胰岛和细胞移植中心是国内为数不多的提供胰岛自体移植全胰腺切除术的医疗中心之一. This innovative dual procedure helps alleviate pain caused by pancreatitis, 同时保持分泌胰岛素的能力,降低患手术性糖尿病的风险.

胰腺切除术 and islet autotransplant

慢性胰腺炎患者在全胰腺切除术后可以选择自体胰岛移植. During an islet autotransplant, 患者自身的胰岛细胞从切除的胰腺中分离出来,然后重新植入患者体内, where they start producing insulin.

这个手术可以预防糖尿病的发展,或者使糖尿病比单独进行胰腺切除术的患者更轻.

While the goal is to eliminate each patient's pain, preserve their pancreatic function and prevent diabetes, 不能保证不会发生糖尿病,因为没有办法在移植前确定患者胰岛的质量.

接受胰腺切除术和胰岛自体移植的患者有50%的机会终生依赖胰岛素, 而只做过胰腺切除术的患者有100%的机会成为永久的胰岛素依赖. 患糖尿病风险最高的患者是那些之前没有做过切除部分胰腺手术的人.

通常, 患者在胰岛自体移植胰切除术后住院2 - 3周. During this time, 患者接受胰岛素滴注,并学习如何在病情发展时控制糖尿病.

当胰岛开始工作时,患者就能减少胰岛素的用量. 一个月内, 通常情况下,胰岛是否工作良好,足以让患者完全停止服用胰岛素,就变得很清楚了. If diabetes develops, 患者与十大赌博平台排行榜密切合作制定胰岛素治疗计划是很重要的.

加州大学旧金山分校健康 medical specialists have reviewed this information. 它仅用于教育目的,并不打算取代您的十大赌博平台排行榜或其他医疗保健提供者的建议. 我们鼓励您与您的供应商讨论您可能遇到的任何问题或疑虑.

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